Structure and function of the reovirus genome.

INTRODUCTION ................ ................................ 483 DISCOVERY OF REOVIRUSES .............................................. 483 STRUCTURE OF THE REOVIRUS PARTICLE .................. ............. 484 REOVIRUS GENOME ................................................ 484 PROTEINS OF REOVIRUS ................................................ 486 INFORMATION CONTENT OF THE 10 REOVIRUS GENES ...... ............ 488 ENZYMES IN REOVIRUS .................................................... 489 TRANSCREPTION OF REOVIRUS RIBONUCLEIC ACID ....... .............. 489 SEQUENCES OF REOVIRUS GENES AND MESSENGER RIBONUCLEIC ACIDS ............................................ 490 TRANSLATION OF REOVIRUS MESENGER RIBONUCLEIC ACIDS ........ 493 ESSENTIAL FEATURES OF THE REOVIRUS MULTIPICATION CYCLE ..... 494 Reovirus Morphogenesis. ..................... ............................. 495 Reovirus DeletionMutants. ................................................. 496 TEMPERATURE-SENSITIVE MUTANTS OF REOVIRUS ...... ............... 496 INTERACTION OF REOVIRUS WITH THE INTACT HOST ...... ............. 497 LITERATURE CITED ......................................................... 498